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生命的基本8和美国成年人慢性病的死亡率
Hongyu Chen1, Haoxian Tang2, Jingtao Huang2
1Department of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.
American journal of nephrology
|August 17, 2023
概括
坚持生活的基本8 (LE8) 准则显著降低了慢性病 (CKD) 患者的死亡风险. 较高的LE8得分与慢性瘤患者全因,心血管疾病和癌症死亡率的降低相关.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 心血管健康 心血管健康
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 影响了大量人口,增加了死亡风险.
- 生命的基本8 (LE8) 是心血管健康的指标.
- 调查LE8对CKD死亡率的影响至关重要.
研究的目的:
- 评估遵守生命的基本8 (LE8) 和慢性病 (CKD) 患者的死亡结果之间的关联.
- 确定较高的LE8分数是否与CKD人口中所有原因,心血管疾病 (CVD) 和癌症死亡率的降低相关.
主要方法:
- 从2005-2018年国家健康和营养调查 (NHANES) 中对22420名美国成年人的分析.
- 根据eGFR和白蛋白与肌素的比率定义的CKD;LE8组件 (饮食,PA,尼古丁,睡眠,BMI,脂质,葡萄糖,BP) 得分为0-100.
- 在2019年12月之前,Cox比例危险回归用于分析与死亡率的关联.
主要成果:
- 较高的LE8得分 (中度和高心血管健康) 与一般人群中较低的CKD患病率有关.
- 慢性病患者的全因和心血管疾病死亡率显著增加.
- 在CKD患者中,每增加10个LE8点就降低了全因 (17%),心血管疾病 (18%) 和癌症 (12%) 的死亡风险,特别是与PA,尼古丁,葡萄糖和BP相关的死亡风险.
结论:
- 较高的遵守生命的基本8 (LE8) 与慢性病 (CKD) 患者的死亡率降低有关.
- 与LS7.7相比,LE8为CKD患者的心血管疾病死亡率提供了优越的风险分层.
- LE8显示了与降低死亡率的显著关联,突出了其在CKD管理中的重要性.
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