突变α-synuclein在单体状态下通过大脑的淋巴系统传播

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Updated: Jul 19, 2025

Technique for Intranasal Administration of α-Synuclein Aggregates
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Technique for Intranasal Administration of α-Synuclein Aggregates

Published on: November 8, 2024

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Kyota Fujita1, Hidenori Homma1, Meihua Jin1

  • 1Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

Cell reports
|August 17, 2023
PubMed
概括

突变的α-synuclein单体在进入神经元后通过大脑传播并形成帕金森病纤维. 这表明一种与聚合物依赖途径不同的新型传播机制.

关键词:
科普:神经科学:神经科学是一门学科.帕金森病是帕金森氏症的一种疾病.聚合方式 聚合方式 聚合方式大脑淋巴系统 大脑淋巴系统一个单质的单质分子.神经退行症的神经退行症神经退行性疾病的神经退行性疾病类蛋白质的传播方式类类物质是什么?蛋白质的传播 蛋白质的传播α-synuclein 是一种同核蛋白.

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