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关于多环性宏分子药物固体稳定性的研究:对甲基可巴胺的案例探索

Zhaoxia Ao1, Shanshan Feng1, Chenyang Zhao1

  • 1School of Chemical Engineering and Technology, State Key Laboratory of Chemical Engineering, Tianjin University, The Co-Innovation Center of Chemistry and Chemical Engineering of Tianjin, Tianjin 300072, PR China.

International journal of pharmaceutics
|August 17, 2023
PubMed
概括

甲基可巴胺 (MeCbl) 是一种维生素B12衍生物,在制药制剂中存在稳定性挑战. 这项研究确定了三种MeCbl水合物形式,并确定了稳定的固态制备的条件,有助于大规模生产.

关键词:
药物结晶 药物的结晶这是一个巨分子分子.甲基可巴胺是什么 甲基可巴胺是什么固态稳定性的稳定性溶酸盐的使用方法

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