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Updated: Jul 19, 2025

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循环瘤细胞衍生的临床前模型:现状和未来前景.

Zuzana Kahounová1, Markéta Pícková1,2,3, Stanislav Drápela1,2,3,4

  • 1Department of Cytokinetics, Institute of Biophysics of the Czech Academy of Sciences, 612 00, Brno, Czech Republic.

Cell death & disease
|August 17, 2023
PubMed
概括

循环瘤细胞 (CTC) 是了解癌症传播和开发新治疗方法的关键. 本综述涵盖了临床前模型,如CTC衍生异种移植,用于研究CTC和推进精确癌症医学.

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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