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Updated: Jul 19, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay

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开发基于库马林的多目标抗乳腺癌药物:合成和分子建模研究

Fiby N Takla1,2, Waleed A Bayoumi1, Shahenda M El-Messery3

  • 1Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.

Scientific reports
|August 17, 2023
PubMed
概括

新的库马林衍生物对乳腺癌细胞系表现出强大的抗癌活性. 化合物8,10和12有效抑制癌细胞增殖和向关键酶,提供有前途的治疗潜力.

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