血清25-基维生素D度与北苏丹成年人高血压之间的关联:基于社区的横截面研究
Ahmed A Hassan1, Omer Abdelbagi2, Osman E Osman3
1Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
BMC cardiovascular disorders
|August 17, 2023
概括
这项研究发现,苏丹成年人中低维生素D水平和高血压之间没有直接联系. 然而,较低的维生素D与较高的缩血压有关,这表明需要进一步调查的复杂关系.
科学领域:
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
- 营养科学 营养科学
背景情况:
- 高血压是一个重要的全球健康问题.
- 25维生素D (25[OH]D) 和高血压之间的关系尚未完全理解.
- 这项研究探讨了居住在苏丹的成年人的相关性.
研究的目的:
- 为了研究血清25(OH) D水平与苏丹成年人高血压之间的关联.
- 探索维生素D状态和血压参数之间的潜在联系.
主要方法:
- 一项基于社区的横截面研究在北苏丹进行.
- 收集的数据包括社会人口统计信息,临床数据,以及通过ELISA测量的血清25...OH) D水平.
- 统计分析涉及多变量逻辑回归和多重线性回归.
主要成果:
- 在391名参与者中,56.0%患有高血压,75.4%患有维生素D缺乏.
- 年龄,女性性别和体重指数与高血压有显著的关联.
- 血清25(OH) D水平与高血压没有显著相关 (AOR=1.01,P=0.317).
- 在血清25(OH) D和静脉血压之间观察到负相关性 (系数=-0.28,P=0.017).
结论:
- 在这个苏丹成年人群中,血清25 ((OH) D水平与高血压没有直接关联.
- 在维生素D和静脉压之间发现了显著的负相关性.
- 需要进一步的研究来阐明维生素D与缩血压之间观察到的关联背后的机制.
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