相关实验视频

Updated: Jul 19, 2025

An Alternative Culture Method to Maintain Genomic Hypomethylation of Mouse Embryonic Stem Cells Using MEK Inhibitor PD0325901 and Vitamin C
11:53

An Alternative Culture Method to Maintain Genomic Hypomethylation of Mouse Embryonic Stem Cells Using MEK Inhibitor PD0325901 and Vitamin C

Published on: June 1, 2018

6.7K

在化学定义的介质中,NELFA和BCL2在小鼠胚胎干细胞中诱导2C类状态

Baojiang Wu1,2, Yanqiu Wang1,2, Xinhua Wei1,2

  • 1The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot, China.

Cell proliferation
|August 18, 2023
PubMed
概括

负延长因子A (Nelfa) 的过度表达促进了小鼠胚胎干细胞 (ESC) 转化为2细胞类 (2C类) 细胞. 与Bcl2的共同过度表达强烈地激活ESC中的全能2C类状态.

更多相关视频

Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency09:07

Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency

Published on: June 10, 2018

10.0K
The use of SC1 Pluripotin to Support mESC Self-renewal in the Absence of LIF05:58

The use of SC1 Pluripotin to Support mESC Self-renewal in the Absence of LIF

Published on: November 18, 2009

10.6K

相关概念视频

Maintenance of the ES Cell State01:14

Maintenance of the ES Cell State

The cells of the blastocyst inner cell mass only remain pluripotent for a short time. This state of pluripotency and self-renewal can be maintained in embryonic stem (ES) cell culture by adding specific chemicals or growth factors to ensure the cells can continue dividing and later differentiate into different cell types. In some cases, the cells are grown on a feeder layer of differentiated cells, which provides the growth factors and extracellular matrix components necessary for stem cell...
2.2K