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大奶粉和早产婴儿:系统性审查

Ethan Slouha1, Zoe S Anderson1, Nana Mansa N Ankrah1

  • 1Anatomical Sciences, St. George's University School of Medicine, True Blue, GRD.

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|August 18, 2023
PubMed
概括

早期给早产婴儿的乳头增强了肠道微生物群和免疫反应,但并没有显著减少NEC,LOS或VAP的发生率. 然而,它确实改善了食时间,缩短了住院时间.

科学领域:

  • 新生儿医学 新生儿医学
  • 免疫学 免疫学 免疫学
  • 微生物组研究 微生物组研究

背景情况:

  • 过早出生的婴儿容易感染诸如死角性肠球炎 (NEC),晚发性败血症 (LOS) 和呼吸机相关肺炎 (VAP) 等感染.
  • 母乳牛奶含有免疫调节因子 (免疫球蛋白,乳酪蛋白,寡糖),支持肠道健康和免疫功能.

研究的目的:

  • 评估早期大奶粉给药对早产婴儿健康结果的影响.
  • 评估对肠道微生物组成的影响,炎症标志物,以及主要新生儿发病率.

主要方法:

  • 使用PubMed,ScienceDirect和ProQuest进行的元分析和实验研究的系统文献综述.
  • 关键词:"乳酪和早产"",乳酪和死性肠球炎".
  • 纳入标准主要集中在检查乳母乳对早产婴儿的影响的研究上.

主要成果:

  • 大奶粉的摄入增加了有益的细菌 (乳酸菌,Bifidobacterium) 和减少了有害的细菌 (摩拉塞拉系,Staphylococcaceae).
  • 唾液分泌IgA水平上升,IL-1b和IL-8下降,而TNF-a和IFN-g与对照组相比较低.
  • 在NEC,LOS或VAP发生率上没有显著差异;然而,观察到改善了完全肠道养的时间和减少了住院时间.
关键词:
大奶粉是什么? 大奶粉是什么? 大奶粉是什么?进口养 进口养 进口养死性肠球炎 (necrotizing enterocolitis) 是一种致死性肠球炎.早产婴儿早产婴儿是什么意思已经有了血症.通过通风机获得的肺炎

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结论:

  • 早期的胆乳给药积极调节早产婴儿的肠道微生物组和免疫状态.
  • 虽然没有减少主要的疾病,但乳酪显示了改善早产婴儿的食耐受性和住院时间的潜在好处.