儿童疹伤寒:印度东部一家三级医院的前性观察研究
Jadab Kumar Jana1, Anusree Krishna Mandal1, Soumya Gayen1
1Pediatrics, Bankura Sammilani Medical College and Hospital, Bankura, IND.
Cureus
|August 18, 2023
概括
儿童的擦伤伤寒表现出各种症状,如发烧,皮疹和器官功能障碍,即使没有治疗. 早期诊断和多西环林治疗对于这种被忽视的热带疾病的更好的结果至关重要.
科学领域:
- 儿童传染病 儿童传染病
- 热带医学 热带医学
- 流行病学 流行病学
背景情况:
- 由*Orientia tsutsugamushi*引起的疹伤寒是一种重新出现的,急性发烧性疾病和被忽视的热带疾病.
- 了解它的临床谱,并发症和儿童死亡率是必不可少的,因为它的各种表现.
研究的目的:
- 为了调查住院儿童的草伤寒的临床多样性,并发症和死亡率.
- 确定关键的临床和实验室发现,表明小儿病患者的湿疹伤寒.
- 评估不同抗生素治疗的有效性和共感染的影响.
主要方法:
- 一年内进行的前性观察性研究.
- 包括206名患有发烧 (≥5天) 和阳性*Orientia tsutsugamushi*测试的儿童 (1个月12岁) 入院治疗.
- 收集有关人口统计,临床症状,实验室结果,共感染,并发症和治疗结果的数据.
主要成果:
- 发烧 (100%) 是普遍的;常见的症状包括肝炎 (49.51%),脸部胀 (39.32%) 和水 (27.18%).
- 典型的实验室发现是贫血 (81.55%),血小板缺血 (49.51%) 和肝酶升高 (ALT 57.28%,AST 63.59%).
- 多西环素比阿齐思罗米辛 (P=0.000) 显著提前显示出发烧分发;肝炎是最常见的并发症 (63.59%).
结论:
- 在患有脑膜炎,毛细血管泄漏,皮疹,结膜堵塞,LRTI,AKI或肝脏功能障碍的发烧儿童中,应怀疑风,特别是在季风后.
- 缺少埃斯卡尔并不能排除灌木风.
- 及时诊断和适当的抗生素治疗,如多西环素,对于减少发病率和死亡率至关重要.
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