在普罗波福-雷米芬坦尼尔麻醉期间以EEG衍生的疼痛值指数为指导对比标准护理:一项随机对照试验
Yu Jiang1, Jian-Ming Ding1, Xi-Xi Hao1
1Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, PR China.
Heliyon
|August 18, 2023
概括
疼痛值指数 (PTI) 引导的止痛疗法显著降低了在麻醉后护理单位 (PACU) 进行补救性止痛的需要. 这种新的方法为手术患者提供了改善的疼痛管理.
科学领域:
- 麻醉学和疼痛管理
- 神经科学是一个神经科学.
- 医疗技术 医疗技术 医学技术
背景情况:
- 疼痛值指数 (PTI) 是一种来自自发电脑电图 (EEG) 波波分析的可感觉的新方法.
- 在预测术后疼痛和血液动力学反应方面,PTI已经显示出准确性.
- 优化术后疼痛管理仍然是一个临床挑战.
研究的目的:
- 评估PTI导向止痛疗法在减少疼痛强度和补救性止痛疗法的有效性.
- 为了比较PTI引导的止痛与在麻醉后护理单位 (PACU) 的标准临床护理.
主要方法:
- 一项随机对照试验,涉及122名接受选择性妇科手术的女性患者.
- 患者被分配到由PTI引导的止痛疗法 (目标PTI 40-65) 或由血液动力学引导的标准护理.
- 主要结局是补救性止痛率;次要结局包括疼痛评分,阿片类药物消耗和压力激素水平.
主要成果:
- 与对照组 (40%) 相比,PTI组的补救性止痛率 (14%) 显着较低.
- 在PTI组的患者在PACU中需要更少的sufentanil.
- 在手术期间摄入雷米芬坦尼尔和普罗波福尔,以及与阿片类药物相关的不良事件在不同组之间是相似的.
结论:
- PTI引导的止痛疗法有效地减少了在妇科手术后的PACU中需要补救性止痛疗法.
- 需要对不同的PTI值和不同人群进行进一步的研究,以确认临床有效性.
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