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针对致病性MHCII类的调节性T细胞:胰岛素表位推迟自发性自身免疫糖尿病

Nyerhovwo Obarorakpor1, Deep Patel1, Reni Boyarov1

  • 1Diabetes Center, Indiana Biosciences Research Institute, Indianapolis, IN, United States.

Frontiers in immunology
|August 18, 2023
PubMed
概括

输注针对胰岛素B:9-23表位特异的工程调节性T细胞 (Tregs) 延迟了小鼠1型糖尿病 (T1D) 的发病. 这种向的Treg疗法通过抑制小岛的自身免疫反应来预防T1D的前景.

关键词:
大型HC II/胰岛素复合体1 型糖尿病 1 型糖尿病抗原特异性免疫疗法是一种抗原特异性免疫疗法.仿制性抗原受体的复制性受体.这是一种单克隆抗体.监管性T细胞监管性T细胞

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