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冠状动脉支架设计对栓塞过器碎片负荷的影响在冠状动脉支架期间

Francesco Squizzato¹, Michele Piazza¹, Edoardo Forcella¹

¹Section of Vascular and Endovascular Surgery (F.S., M.P., E.F., E.C.C., F.G., M.A.), Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padua, Italy.

|August 18, 2023

概括

微网状支架 (MMS) 在动脉支架时显示出较低的栓塞率,相比于开放细胞 (OCS) 和闭细胞 (CCS) 支架. 这种减少的栓塞过器碎片 (EFD) 负载在特定的斑块类型中尤为明显.

科学领域:

心血管外科心血管外科
干预心脏病学干预心脏病学
生物材料科学生物材料科学

背景情况:

动脉支架的设计是影响动脉支架期间栓塞风险的潜在因素.
评估这种风险对于患者安全和程序结果至关重要.

研究的目的:

用不同的支架设计来比较 carotid 动脉支架期间栓塞物质的数量.
评估与开放细胞 (OCS),闭细胞 (CCS) 和微混凝土支架 (MMS) 相关的栓塞过器碎片 (EFD) 负载.

主要方法:

一个单一中心的回顾性研究包括481名患者,这些患者接受了无症状心动脉狭窄 (>70%) 的心动脉支架.
支架根据设计 (OCS,CCS,MMS) 进行分类,并采用远距离镜保护.
栓塞物质被量化,EFD负荷被计算为主要终点.

主要成果:

与OCS (9.1±14.5%) 和CCS (7.9±14.0%) (P<0.001) 相比,micromesh支架 (MMS) 的EFD负荷明显较低 (5.0±9.1%).
MMS更频繁地与没有栓塞物质的过器相关 (41%对30%的OCS,13%的CCS).
低EFD负载的MMS被观察到在hypoechogenic斑块,斑块>15毫米,以及在手术前缺血性脑损伤的患者.

结论:

微网状支架 (MMS) 与栓塞率降低和较低的栓塞过器碎片 (EFD) 负载有关.
在降低栓塞的MMS的好处是特别显著的hypoechogenic或长斑的患者,以及那些以前无症状的缺血性脑损伤.

关键词:

動脈動脈 - 頸動脈動脈动脉狭窄症是什么意思患者患者患者患者患者患者患者危险的风险危险的风险支架是一种支架.一次性中风中风中风中风中风

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