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Updated: Jul 19, 2025

Efficient Generation and Editing of Feeder-free IPSCs from Human Pancreatic Cells Using the CRISPR-Cas9 System
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基于CRISPR/Cas9的细胞衍生细胞外矩阵的精确设计策略,用于调节神经干细胞功能.

Yuanxin Zhai1, Lingyan Yang1, Wenlong Zheng2

  • 1CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics. Chinese Academy of Sciences, Suzhou, Jiangsu 215123, China. lyy2013@sinano.ac.cn.

Biomaterials science
|August 18, 2023
PubMed
概括

研究人员设计了一种来自细胞的细胞外基质 (ECM),可以增强生长因子的结合. 这种功能性ECM支持神经干细胞 (NSC) 的维护,增殖和分化,提供生物材料应用.

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相关概念视频

CRISPR01:59

CRISPR

Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
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