缺血性单眼视力丧失和并发性脑缺血的患病率和危险因素
Cathy E Smith1,2, Juraj Kukolja1,2
1Department of Neurology and Clinical Neurophysiology, Helios University Hospital Wuppertal, Wuppertal, Germany.
European stroke journal
|August 18, 2023
概括
老年患者 (66岁以上) 患有与心脏相关的单眼视力丧失和之前的中风,患静音脑缺血的风险更高. 大脑MRI可以在这些人身上检测出这种情况.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
背景情况:
- 缺血性单眼视力丧失 (MVL) 可能是潜在的脑血管疾病的迹象.
- 沉默性脑缺血症 (SBI) 通常不会被发现,但可能会增加中风风险.
研究的目的:
- 确定患有缺血性单眼视力丧失的患者同时出现无症状脑缺血的预测因素.
- 确定与此患者群体中静音脑缺血相关的患病率和心血管风险因素.
主要方法:
- 一个单眼视力丧失患者的回顾性队列研究,他们被录取到Helios大学医院Wuppertal (2016-2020).
- 纳入标准:确认了短暂单眼视力丧失 (MVL) 或视网膜动脉封闭 (RAO) 的诊断,并在10天内进行大脑MRI.
- 沉默性脑缺血症 (SBI) 由MRI扩散限制定义;使用后勤回归和人工神经网络分析的预测因素.
主要成果:
- 在475名患者中,有114名患者符合纳入标准;17%的MRI检测到SBI.
- 平均年龄为67.7岁;48.2%是男性;47.4%有RAO.
- 预测SBI的预测因素包括年龄67岁以下,MVL的心脏病因,以及脑缺血史.
结论:
- 66岁以上的患者,怀疑心血管栓塞导致RAO,以及脑缺血病史的患者更有可能患有SBI.
- 大脑MRI是检测SBI的宝贵工具,特别是在这些预测因素识别的高风险患者中.
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