从无线电频率鼻腔气道重塑装置进行温度配置测量
Eric H Abello1,2, Theodore V Nguyen1, Katelyn K Dilley1
1Beckman Laser Institute and Medical Clinic, Irvine, California, USA.
The Laryngoscope
|August 18, 2023
概括
鼻腔气道阻塞的射频治疗可能会导致软骨的热损伤. 这项研究使用红外成像和计算建模来绘制温度变化图,并预测高达1.4mm深度的软骨细胞死亡.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 生物医学工程 生物医学工程
- 医学物理 医学物理
背景情况:
- 鼻呼吸道阻塞 (NAO),通常是由鼻塌陷 (NVC) 引起的,影响呼吸.
- 双极射频 (RF) 设备被用来通过加热上侧软骨 (ULC) 来治疗NAO.
研究的目的:
- 使用红外 (IR) 辐射计测量鼻腔组织的温度升高.
- 在射频处理过程中绘制温度的空间和时间演变图.
- 以计算方式建模热传递和组织损伤.
主要方法:
- 实验:猪鼻腔隔膜部分 (厚度为1mm和2mm) 用射频装置加热.
- 红外 (IR) 成像捕捉了背面温度变化.
- 计算:有限元建模分析了使用阿雷尼乌斯速率过程的热传递和组织损伤.
主要成果:
- 背面的最高温度达到49.57°C (1mm隔膜) 和42.21°C (2mm隔膜).
- 红外成像提供了空间和时间温度分布图.
- 计算模型在18秒的射频治疗后,预测了长细胞死亡,深度高达1.4毫米.
结论:
- 射频设备的使用会产生热谱,这可能会导致软骨的热损伤.
- 计算建模表明,潜在的冠状细胞死亡范围远远低于治疗表面.
- 需要进行进一步的研究,以优化剂量测量和尽量减少在NAO的射频治疗期间的潜在伤害.
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