七节痕作为一个障碍,以左捆分支区域步伐节奏
Nadine Ali1, Ahran D Arnold1, Alejandra A Miyazawa1
1National Heart and Lung Institute, Imperial College London, London, UK.
Pacing and clinical electrophysiology : PACE
|August 18, 2023
概括
七面痕显著阻碍了成功的左捆分支区域节奏 (LBBAP) 部署. 对痕范围的心脏MRI评估对于规划LBBAP程序至关重要,特别是在心脏再同步治疗中.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 心脏成像 - - 心脏成像
背景情况:
- 左捆支部区域节奏 (LBBAP) 越来越多地用于胸心节奏和心脏再同步治疗.
- 成功的LBBAP植入可能具有挑战性,据报道植入失败.
研究的目的:
- 调查隔膜痕对LBBAP植入成功率的影响.
- 确定程序前痕评估是否可以预测LBBAP植入物结果.
主要方法:
- 对接受LBBAP治疗的患者进行前性研究,以进行胸肌节律调节或CRT.
- 术前心脏MRI与晚期加多增强用于痕评估.
- 试图通过使用无光的横截面方法进行LBBAP植入.
主要成果:
- 在35名患者中,成功的部署在86%的患者中实现.
- 14%的患者出现了植入失败.
- 广泛的隔膜痕 (中位数增强54%) 与较少广泛的痕 (中位数增强8%) 相比,与更高的植入失败率有关,p < .001.
结论:
- Septal 痕 通过穿越路线成功部署 LBBAP 的存在重大挑战.
- 患有广泛隔膜痕的患者可能需要替代的植入策略或工具来获得成功的LBBAP.
相关概念视频
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
16
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
16
01:22Mitral Stenosis I: Introduction
16
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
16