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Updated: Sep 9, 2026

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在中国的 Orofacial 裂和相关异常的异质性

Leheng Jiang¹, Chanyuan Jiang, Yongqian Wang

¹Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

The Journal of craniofacial surgery

|August 18, 2023

概括

这项研究详细介绍了中国的口腔裂,发现男性有更严重的病例,并强调了相关心脏缺陷的高率. 微型裂唇 (CL) 需要临床关注,因为它的流行率和相关的形.

科学领域:

医学研究医学研究
流行病学流行病学
遗传学遗传学是一个

背景情况:

耳鼻裂是常见的出生缺陷,但来自中国的详细流行病学数据很少.
了解描述性流行病学和相关的形是有效管理的关键.

研究的目的:

提供详细的临床分类的口腔裂,包括微型裂唇 (CL).
报告在中国主要裂手术单位治疗的患者相关的发育不良.

主要方法:

718名接受初级裂修复的患者的回顾性审查 (2016年12月 - 2023年4月).
对性别分布,裂横向性和相关先天性形的频率的分析.

主要成果:

男人显示出更严重的裂的比例更高.
单边CL的左至右比为1.85:1.
相关的形因裂类型而异,只有口裂的频率最高 (30.9%).
在69名患者中观察到的98种形中,心血管异常是最常见的 (39.1%).
微型CL的患病率增加,并呈现出与明显CL相似的形率.

结论:

这项研究提供了关于中国口腔裂的重要流行病学数据.
由于心脏缺陷的高发病率,建议进行例行心声回声扫描.
由于其流行率和相关异常,微型CL需要增加临床关注.

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