在重复心脏手术后开发和验证肺炎的诺莫格拉姆模型
Dashuai Wang1, Yixue Li2, Weiyong Sheng2
1Department of Cardiovascular Surgery.
Journal of cardiovascular medicine (Hagerstown, Md.)
|August 18, 2023
概括
这项研究确定了重复心脏手术后手术后肺炎 (POP) 的关键风险因素. 一个经过验证的名录模型有助于预测POP风险并指导个性化的患者治疗.
科学领域:
- 心脏病学 心脏病学
- 胸部外科手术 胸部外科手术
- 临界护理医学 临界护理医学
背景情况:
- 手术后肺炎 (POP) 是心脏重复手术后的一种严重并发症.
- POP与患者不良结果和医疗保健成本增加有关.
研究的目的:
- 在接受重复心脏手术的患者中确定POP的独立风险因素.
- 在这个患者群体中开发和验证POP的预测模型.
主要方法:
- 对接受重复心脏手术 (2016-2019) 的成年患者进行了回顾性分析.
- 患者被分为训练 (2:1比) 和验证组.
- 用单变量和多变量分析来识别预测因素;构建和验证了一个名ogram.
主要成果:
- 手术后的肺炎发生在19.1%的患者 (72/376).
- 确定了独立的风险因素:年龄,慢性阻塞性肺病,血清肌素和手术内输血量.
- 命名图表显示了良好的区分 (c指数0.86培训,0.78验证) 和校准.
结论:
- 在重复心脏手术后预测POP的nomogram模型已成功开发和验证.
- 该模型显示了风险分层和个性化治疗策略的良好的临床实用性.
- 这种工具可以帮助减轻重复心脏手术的患者的不良事件.
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