良性外围神经瘤:一个跨学科的诊断和治疗挑战
Anne-Kathrin Uerschels1,2, Nora F Dengler3, Mehdi Chihi1,2
1Department of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Neurosurgical review
|August 18, 2023
概括
良性外周神经膜瘤 (bPNSTs) 的错误诊断影响了近一半的患者,导致延迟或有害的治疗. 早期和准确的诊断对于有效管理这些罕见的神经瘤至关重要.
科学领域:
- 神经外科 神经外科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 良性外围神经膜瘤 (bPNSTs) 是外围神经的罕见病变.
- 不同类型的症状和可变的管理概念使bPNST的诊断和治疗变得复杂.
- 错误诊断可能导致治疗不当,导致严重的功能缺陷和慢性疼痛.
研究的目的:
- 分析bPNST患者先前误诊和治疗错误的发生率和影响.
- 评估错误的初始诊断对患者结果的影响.
- 突出需要在bPNST管理中提高诊断准确度.
主要方法:
- 在2015年1月至2021年7月期间为bPNSTs治疗的85名患者的回顾性分析.
- 评估人口统计,瘤特征,症状,诊断间隔和治疗细节.
- 特别关注最初的错误诊断,不适当的医疗治疗以及随后的结果.
主要成果:
- Schwannoma 是最常见的 bPNST (75.3%).
- 在44.7%的患者中出现了不正确的初级诊断.
- 错误诊断导致了不理想的治疗 (28.9%),不必要的诊断 (18.5%),以及严重的神经缺陷 (26.3%) 的不适当的手术.
结论:
- 几乎一半的bPNST患者经历了最初的诊断错误.
- 错误诊断显著延迟了因果治疗或导致有害的干预措施.
- 改进的诊断策略对于预防虐待和改善bPNST患者的治疗结果至关重要.
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