评估艾滋病毒老龄化秘鲁妇女的区域身体组成,身体功能和肉症:一个横截面研究
Diego M Cabrera1,2,3, Mijahil P Cornejo4, Yvett Pinedo5
1Department of Internal Medicine, Section of Rheumatology, Allergy and Immunology, Yale School of Medicine, New Haven, Connecticut, United States of America.
PLOS global public health
|August 18, 2023
概括
在秘鲁,艾滋病毒感染的老年女性表现较差的体力表现和身体成分的改变,干部脂肪影响了移动性. 需要进一步的研究,以指导萨科佩尼亚和功能衰退的预防策略.
科学领域:
- 老年学是一门学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 对于接受高活性抗逆转录病毒疗法 (ART) 的艾滋病毒感染者 (PLWHIV) 来说,慢性疾病管理至关重要,特别是在资源有限的环境中.
- 身体组成的变化,包括脂肪和肌肉的再分配,是艾滋病毒感染妇女在ART的担忧.
- 关于拉丁美洲和加勒比地区这些结果的数据有限.
研究的目的:
- 探索秘鲁艾滋病毒感染和不感染的老年女性的身体组成,身体表现和肉症.
- 确定艾滋病毒感染妇女的身体组成和身体功能之间的关联.
主要方法:
- 在秘鲁,对40岁以上的艾滋病毒感染者和没有艾滋病毒感染者的横截面研究.
- 双X射线吸收计测试身体组成 (瘦身量,脂肪量).
- 物理性能和力量的短物理性能电池 (SPPB) 和动力测量;萨科佩尼亚的EWGSOP标准.
主要成果:
- 艾滋病毒感染女性的SPPB得分明显较低 (9.9比10.8).
- 体脂肪量和年龄较大与艾滋病毒感染妇女的身体表现有负相关性.
- 干部脂肪质量和上肢瘦肉质量分别预测了SPPB和握力.
结论:
- 与没有艾滋病毒的妇女相比,秘鲁的艾滋病毒感染妇女的身体表现较差.
- 身体成分,特别是干脂肪质量,是影响这个人群身体功能的一个关键因素.
- 该地区需要进行前性研究,以制定针对性预防sarcopenia和功能衰退的指导方针.
更多相关视频
14:39Semi-Targeted Ultra-High-Performance Chromatography Coupled to Mass Spectrometry Analysis of Phenolic Metabolites in Plasma of Elderly Adults
Published on: April 22, 2022
4.0K
07:27Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
Published on: October 6, 2016
10.3K
相关概念视频
01:19The Effect of Aging on Tissues
2.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.1K
01:26Aging
86
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
86