在接受抗血栓治疗的患者中,经皮切经肝胆囊排水和吸入后的术后出血
Takayuki Iwamoto1, Takahiro Suda1, Takanori Inoue1
1Department of Gastroenterology and Hepatology, Kansai Rosai Hospital, Hyogo, Japan.
PloS one
|August 18, 2023
概括
在急性胆囊炎的皮肤透过肝胆囊干预期间持续服用多种抗血栓药物会增加术后出血的风险. 停药或单药使用可以减轻这种出血风险.
科学领域:
- 干预性放射学 干预性放射学
- 胃肠病学 胃肠病学
- 心脏病学 心脏病学
背景情况:
- 急性胆囊炎通常需要干预,患者经常接受抗血栓治疗.
- 皮肤透过肝胆囊的干预是急性胆囊炎的常见程序.
- 在这些干预中,外科手术期间的抗血栓药物管理对出血风险的影响尚未完全理解.
研究的目的:
- 为了研究抗血栓治疗与血液出血风险之间的关联,在接受急性胆囊炎的皮肤经肝胆囊干预的患者中.
- 确定特定的抗血栓药物疗法,这些疗法会增加术后出血的风险.
主要方法:
- 对194名患有急性胆囊炎的患者进行了回顾性分析,这些患者接受了皮肤透过肝的胆囊干预.
- 根据抗血栓治疗,患者被分为四组:没有,停药,单药继续使用或多药继续使用.
- 多变量逻辑回归用于评估术后出血风险.
主要成果:
- 显著出血发生在10.3%的患者,严重出血发生在3.1%的患者.
- 与没有先前治疗的患者相比,在外科手术期间继续服用多种抗血栓药物的患者有显著高的显著出血率 (P = 0.006).
- 持续服用多种抗血栓性药物被确定为严重出血的独立风险因素.
结论:
- 术后继续多种抗血栓药物是经皮切经肝胆囊干预后术后出血的重要危险因素.
- 在接受这些手术的患者中,仔细考虑抗血栓药物管理至关重要.
- 进一步的研究可能会探索最佳的抗血栓策略,以平衡血栓和出血风险.
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