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Updated: Jul 19, 2025

Ex Utero Electroporation and Organotypic Slice Culture of Mouse Hippocampal Tissue
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在正在发育的海马原体中,通过LIM-HD转录因子LHX2调节染色质可访问性和基因表达

Varun Suresh1, Bhavana Muralidharan1,2, Saurabh J Pradhan3

  • 1Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai, India.

PLoS genetics
|August 18, 2023
PubMed
概括

转录因子LHX2通过调节发育中的海马体 (Hcp) 中的基因表达和染色质可访问性来独特地塑造海马体的发育,使其与新皮质原始体 (Ncp) 区别开来. 这项研究为早期海马神经发育提供了机制性的见解.

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