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Updated: Jul 19, 2025

Detection of the Genome and Transcripts of a Persistent DNA Virus in Neuronal Tissues by Fluorescent In situ Hybridization Combined with Immunostaining
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TREM2在微质中受到HSV1的下调,并参与大脑中的抗病毒防御

Stefanie Fruhwürth1,2, Line S Reinert3, Carl Öberg2

  • 1Department of Rheumatology and Inflammatory Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

Science advances
|August 18, 2023
PubMed
概括

TREM2 (在骨髓细胞2表达的触发受体) 对于微质对大脑中的简单疹病毒1型 (HSV1) 的抗病毒防御至关重要. 它的缺乏会损害病毒清除,增加感染易感性,可能与阿尔茨海默氏症有关.

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