一种用丝网打印的银电极测定尿样和药品片中的囊的电压计方法
Fang-Ci Kuo1, Chiung-Yao Huang1, Yu-Tung Lin1
1Department of Medical Applied Chemistry, Chung Shan Medical University, Taichung 402, Taiwan.
Journal of pharmaceutical and biomedical analysis
|August 18, 2023
概括
一种新的电压测量方法准确地测量了尿液中的囊水平,有助于囊尿的管理和药品质量控制. 这种快速的技术可在两个样本中提供可靠的囊检测.
科学领域:
- 分析化学 分析化学
- 临床诊断 临床诊断 临床诊断
- 生物医学工程 生物医学工程
背景情况:
- 尿道囊的升高与囊石的形成有关.
- 精确的囊水平的确定对于管理囊性尿症和监测囊药物治疗至关重要.
- 现有的方法可能缺乏及时临床和制药应用所需的速度或效率.
研究的目的:
- 开发一种快速高效的电压计量方法来量化尿囊.
- 为了验证方法的准确性和可靠性,对生物样本和制药产品.
- 为临床诊断囊尿和基于囊的药物的质量控制提供一个有价值的工具.
主要方法:
- 使用商业屏幕打印的银电极建立了电压传感方法.
- 该方法的性能通过校准曲线生成和检测极限确定来评估.
- 对人类尿样和药用囊片进行了测试,以评估康复率.
主要成果:
- 开发的电压计量方法实现了0.65mg/dL的检测极限.
- 对于尿样,观察到89%至109%之间的令人满意的恢复率.
- 对于药物片中的囊,获得了优异的恢复率,从98%到101%不等.
结论:
- 已建立的电压计量方法为确定囊水平提供了快速而准确的手段.
- 该技术适用于囊尿患者的临床诊断和药物配方质量控制.
- 该方法提供了一种有价值的分析工具,用于改善患者管理和确保药物疗效.
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