建筑湿地的抗生素耐药性基因:驱动指标和风险评估
Zhenxiong Zhao1, Yuxuan Zhang2, Ruizhi Liu2
1State Environmental Protection Key Laboratory of Estuarine and Coastal Environment, State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environment Sciences, Beijing 100012, PR China; College of Resources and Environment, Yunnan Agricultural University, Kunming, Yunnan 650201, PR China.
Journal of hazardous materials
|August 18, 2023
概括
建筑湿地 (CWs) 在温暖的季节显示出更高的抗生素耐药性基因 (ARGs) 和移动遗传元素 (MGE). 电压线有效地减少了沿着处理梯度的ARG风险,温度是关键驱动因素.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 水处理工程水处理工程
背景情况:
- 建筑湿地 (CWs) 对于废水处理至关重要,但也促进了抗生素耐药性基因 (ARGs) 的传播.
- 了解影响ARG及其相关风险的因素在CW中对于有效管理至关重要.
研究的目的:
- 研究CW中的ARG和移动遗传元素 (MGE) 的季节性变化和空间分布.
- 确定驱动CW系统中ARG丰度和风险的关键环境因素.
主要方法:
- 在不同季节和沿着CW处理梯度的ARG和MGE丰度的量化.
- 对ARG,MGE和细菌的季节性变化和共发生模式的分析.
- 应用部分最小方程路径建模 (PLSPM) 来确定驱动因素.
主要成果:
- 在春季和夏季,ARG和MGE的丰度显著增加.
- 环境梯度对ARG/MGE丰度没有显著的影响从流入到流出.
- 病原细菌对ARG宿主的比率和ARG风险指数在梯度上显著下降,表明CW作为ARG屏障.
- 温度成为ARG的主要驱动因素,其次是MGE和细菌群落.
结论:
- 季节性变化,特别是温度,显著影响CW中的ARG动态.
- 建筑湿地有效地减轻了在处理过程中的ARG转移风险.
- 温度,MGEs和细菌组成是评估和控制CW中ARG的关键指标.
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