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Updated: Jul 19, 2025

Identification of Circular RNAs using RNA Sequencing
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Identification of Circular RNAs using RNA Sequencing

Published on: November 14, 2019

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圆形RNA的黑暗面,这是基因组不稳定的新驱动力

Ajit Kumar Sharma1, Anish Thomas1

  • 1Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

Cell chemical biology
|August 18, 2023
PubMed
概括

循环RNAs (circRNAs) 可以形成DNA杂交,驱动MLL/KMT2A中的遗传重组. 这一发现揭示了侵袭性急性白血病和新的治疗点.

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