1型糖尿病成年人发生饮食障碍的倾向:每日多次注射和连续皮下胰岛素输注之间的比较
Caterina Policola1, Enrico Di Stasio2, Alessandro Rizzi3
1Unit of Endocrinology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University School of Medicine, Rome, Italy.
Diabetes research and clinical practice
|August 18, 2023
概括
与健康个体相比,患有1型糖尿病 (T1DM) 的成年人对饮食障碍的倾向略高,尽管不显著. 多次每日注射 (MDI) 或胰岛素 (CSII) 等治疗方法没有影响这种倾向.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 行为科学 行为科学
背景情况:
- 第1型糖尿病 (T1DM) 管理需要对心理健康给予密切关注.
- 饮食障碍 (ED) 和身体不满是慢性疾病中的潜在问题.
- 了解T1DM中ED倾向对于全面的患者护理至关重要.
研究的目的:
- 评估1型糖尿病 (T1DM) 的成年人的饮食障碍 (ED) 倾向和身体不满.
- 为了比较T1DM患者使用多次每日注射 (MDI) 与持续皮下胰岛素输注 (CSII) 之间的ED倾向.
- 评估ED倾向与健康受试者 (HS) 相比的差异.
主要方法:
- 一个单心的,横截面的,观察性研究设计.
- 包括162名患有T1DM的成年人和50名健康受试者 (HS).
- 使用身体形状调查问卷 (BSQ) 和饮食障碍清单-3 (EDI-3) 来评估ED倾向.
主要成果:
- 在T1DM患者和HS患者之间,BSQ得分没有显著差异.
- 与HS (8%) 相比,T1DM患者 (16%),在BSQ类1中得分的比例更高.
- 与CSII使用者相比,T1DM患者在MDI上表现出更高的完美主义倾向和Bulimia趋势.
结论:
- 虽然在统计学上不显著,但T1DM患者与对照人群相比,对ED倾向的风险略有增加.
- 胰岛素输送方法 (MDI与CSII) 在T1DM中没有显著影响ED倾向.
- 完美主义在MDI的T1DM患者中成为一个独特的特征.
相关概念视频
Insulin: Dosing Regimen and Adverse Effects
205
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
205
Diabetes Mellitus: Overview and Type I Subtype
2.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.8K
Insulin Formulations: Types and Delivery
226
Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
Short-acting insulins are divided into...
Short-acting insulins are divided into...
226
Diabetes Mellitus: Type 2 and Gestational
2.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.5K
Diabetes: Symptoms, Diagnosis, and Complications
588
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
588
Diabetes: Management and Pharmacotherapy
310
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
310


