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Updated: Jul 18, 2025

Growth-based Determination and Biochemical Confirmation of Genetic Requirements for Protein Degradation in Saccharomyces cerevisiae
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在Saccharomyces cerevisiae中C端序列稳定性分析揭示了保护性蛋白质质量控制途径

Sophia Hasenjäger1, Andrea Bologna2, Lars-Oliver Essen3

  • 1Department of Biology/Genetics, Philipps-University Marburg, Marburg, Germany.

The Journal of biological chemistry
|August 18, 2023
PubMed
概括

蛋白质质量控制通过检查其C端序列来识别和降解有缺陷的蛋白质. 这项研究揭示了蛋白质末端的特定氨基酸模式,这些蛋白质标志着不稳定性,指导降解途径.

关键词:
C 终点 C 终点视觉遗传学 视觉遗传学蛋白质酶体蛋白质组是什么蛋白质降解 蛋白质降解蛋白质质量控制 蛋白质质量控制蛋白质溶解过程中的蛋白质溶解.无处不在的蛋白酶体系统

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