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Updated: Jun 14, 2026

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Ag2S生物相容组合作为双OCT对比剂和NIR眼镜成像探针

Amalia Coro1, Ada Herrero Ruiz2,3, Mateo Pazo-González4,5,6

  • 1Instituto de Ciencia de Materiales de Madrid, CSIC, C/ Sor Juana Inés de la Cruz, 3, 28049, Madrid, Spain.

Small (Weinheim an der Bergstrasse, Germany)
|August 18, 2023
PubMed
概括

硫化银纳米粒子提供双模式眼睛成像. 这些生物相容的纳米粒子增强了光学连贯性断层扫描的对比度,并使近红外成像能够改善眼睛诊断.

关键词:
光成像成像技术的使用.多模式对比剂 多模式对比剂光学连贯性断层扫描技术银硫化物纳米颗粒 银硫化物纳米颗粒

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Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...