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对成年人中Secondum心房隔膜缺陷的多个或单个装置关闭的系统审查

Ali Abdul Jabbar¹, Mohammad Jaradat², Mohanad Hasan³

¹Section of Interventional Cardiology, Cardiology Department, John Ochsner Heart and vascular Institute, Ochsner Clinic Foundation, New Orleans, LA, United States of America; The Tampa Bay Heart Institue at HCA Florida Northside Hospital, University of South Florida Morsani College of Medicine, HCA West FL Division GME Program, St. Petersburg, FL, United States of America.

Cardiovascular revascularization medicine : including molecular interventions

|August 18, 2023

概括

在成年人中,对心房隔膜缺陷 (ASD) 的多重设备关闭 (MDC) 与单个设备关闭 (SDC) 一样安全有效. 这次审查发现,MDC和SDC策略之间的并发症,心律失常或残留分流率没有显著差异.

科学领域:

心脏病学心脏病学
干预心脏病学干预心脏病学
医疗器械医疗器械

背景情况:

前庭隔膜缺陷 (ASD) 是一种常见的先天性心脏病.
多重设备关闭 (MDC) 是成人复杂自闭症的新兴策略.
与单个设备关闭 (SDC) 相比,MDC的安全性和有效性在患有 ostium secundum 缺陷的成年人中尚不清楚.

研究的目的:

为了比较MDC与SDC的安全性和有效性,用于成人 ostium secundum ASDs.
评估两种关闭策略之间的并发症发生率,心律失常率和残留分流率.

主要方法:

一个系统的审查和元分析,遵循PRISMA指南.
数据库的文献搜索和手动搜索截至2017年6月30日.
对MDC和SDC组的整体并发症,心律失常发病率和残留分流率的聚合分析.
基平方分析以确定统计学意义 (p < .050).

主要成果:

分析了20项涉及MDC组147名患者和SDC组1706名患者的研究.
在MDC和SDC之间,在整体并发症发生率 (p = .259) 或心律失常发生率 (p = .568) 中没有发现显著差异.
剩余的分流率是可比的,在SDC组为4.10%,在MDC组为6.80% (p = .122).

结论:

皮穿式MDC用于ASD似乎是一种安全有效的替代SDC.
在与设备相关的并发症和技术成功方面,MDC表现出与SDC相似的结果.
需要进一步的前性注册表数据和随机试验来确定MDC在ASD关闭方面的长期结果.

关键词:

阿姆普拉特泽隔膜封闭器封闭器前庭隔膜缺陷在前庭隔膜缺陷前庭隔膜缺陷关闭闭关闭的缺陷多重心房隔膜缺陷多重心房隔膜缺陷

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