跨腹膜与跨直肠磁共振和超声波图像融合前列腺活检:一个对照对比对比的对比
Masatomo Kaneko1,2, Luis G Medina1, Maria Sarah L Lenon1,3
1Center for Image-Guided Surgery, Focal Therapy and Artificial Intelligence for Prostate Cancer, USC Institute of Urology, 1441 Eastlake Ave, Suite 7416, Los Angeles, CA, 90089, USA.
Scientific reports
|August 18, 2023
概括
跨 (TP) 前列腺活检 (PBx) 提供了与跨直肠 (TR) 方法相比较的癌症检测,癌症核心长度和参与度的显著改善. 这项研究强调TP PBx是诊断临床显著前列腺癌 (CSPCa) 的有效替代品.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 前列腺癌的诊断依赖于准确的活检技术.
- 跨 (TP) 和跨直肠 (TR) 方法用于MRI/TRUS融合前列腺活检 (PBx).
- 将TP与TR PBx的疗效和结果进行比较对于优化患者护理至关重要.
研究的目的:
- 为了比较TP和TRMRI/TRUS融合PBx之间的临床显著前列腺癌 (CSPCa) 的检测率.
- 为了评估两种活检方法之间的癌症核心长度和参与差异.
- 为了确定CSPCa检测的预测因子,在接受融合PBx的患者中进行检测.
主要方法:
- 一项比较研究将168名TP PBx患者与336名TR PBx患者根据PSA,前列腺体积 (PV) 和PIRADS得分进行了匹配.
- 从PIRADS 3-5病变中进行了系统和目标活检.
- 用单变量和多变量分析来评估结果,统计显著性设置为p < 0.05.
主要成果:
- 对于PIRADS 1-5的病变,CSPCa的检测率在TP和TR PBx之间是相似的 (例如,PIRADS 3-5的59%与60%).
- 与TR PBx相比,TP PBx的最大癌症核心长度 (11mm与9mm相比;p=0.02) 和癌症核心参与度 (83%与65%相比;p<0.001) 高得多.
- 年龄,PSA,PV,数字直肠检查结果和PIRADS得分是CSPCa检测的独立预测因素.
结论:
- 跨膜MRI/TRUS融合PBx提供与跨直肠PBx可比的CSPCa检测率.
- TP PBx产生更大的前列腺癌核心长度和更大的核心参与,可能提供更全面的诊断信息.
- 这些发现支持TP PBx作为前列腺癌诊断中的一个有价值的技术.
相关概念视频
01:27Imaging Studies IV: Magnetic Resonance Imaging
26
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
26
01:24Magnetic Resonance Imaging
5.2K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.2K
01:25Ultrasound II: Endoscopic Ultrasound and FibroScan
139
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Endoscopic Ultrasound (EUS):
139
01:17Ultrasonography
4.6K
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...
During an ultrasonography procedure, a handheld device called...
4.6K