镜头因子作为主要角度关闭的基本机制,与视镜可视化的纤毛体过程
Hatice Tekcan1, Mehmet Serhat Mangan2, Gökhan Celik3
1Ophthalmology Department, University of Health Sciences, Haydarpasa Numune Research and Training Hospital, Tıbbiye Street, No: 40, Uskudar, Istanbul, Turkey.
Japanese journal of ophthalmology
|August 18, 2023
概括
主角关闭 (PAC) 眼睛中可见的状体过程与较小的轴长和前腔深度相关,但镜片厚度更大. 这表明透镜拥挤是PAC病理生理学的关键因素.
科学领域:
- 眼科医生 眼科 眼科
- 前段成像前段成像的使用
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 主角闭合 (PAC) 是不可逆转失明的重要原因之一.
- 了解导致PAC的解剖学因素对于有效管理至关重要.
- 在视镜中可视化体过程 (CBP),可以提供有关PAC机制的见解.
研究的目的:
- 为了比较前段参数在初级角度关闭 (PAC) 眼睛和没有gonioscopically可视化的体过程 (CBP).
- 在PAC患者中确定与可见CBP相关的解剖学差异.
主要方法:
- 这是一项前性,观察性,比较性临床研究,涉及89名PAC患者.
- 详细的眼科检查,包括视镜和超声波生物显微镜.
- 测量前腔深度 (ACD),前腔宽度,镜片厚度 (LT),镜片 (LV),瞳孔直径,镜片轴长系数 (LAF) 和相对镜片位置 (RLP).
主要成果:
- 与PAC-CBP组相比,具有可见CBP的眼睛 (PAC+CBP组) 的轴长和ACD明显较小.
- 在PAC+CBP组中,LT,LV和LAF显著增加.
- 在LAF中,与可见CBP的关联最强 (odds比率=141.70,p=0.002).
结论:
- 在PAC眼睛中CBP的镜可视化表明前段拥挤,特别是与镜头相关的因素,作为主要的潜在机制.
- 可见的CBP可以作为预测PAC病理生理学的实际镜标记.
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