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Updated: Jul 18, 2025

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

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降低移植后的环胺剂量与外周血液干细胞平分异性移植中的抗细胞球蛋白

Rémy Duléry1,2, Florent Malard3,4, Eolia Brissot3,4

  • 1Department of Clinical Hematology and Cellular Therapy, Sorbonne University, Saint-Antoine Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France. remy.dulery@aphp.fr.

Bone marrow transplantation
|August 18, 2023
PubMed
概括

将移植后的循环胺 (PT-Cy) 剂量降低到70 mg/kg,对于接受单一血型细胞移植 (HCT) 的老年人或心脏病患者来说是安全的. 这种剂量减少可以改善恢复和生存,同时降低毒性风险.

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In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

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