COVCOG:在认知与情感管理精神教育计划之后,即时和长期的认知改善 - - 在患有神经心理困难的COVID患者中进行的一项随机试验
Sylvie Willems1,2, Vincent Didone3, Carmen Cabello Fernandez3
1Psychology and Neuroscience of Cognition Unit, Université de Liège, Place Des Orateurs, 1, B33 4000, Liège, Belgium. Sylvie.willems@uliege.be.
BMC neurology
|August 18, 2023
概括
这项研究比较了长期COVID认知困难的认知干预和认知行为咨询. 它的目的是找到最有效的非药理方法来改善生活质量.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 传染性疾病 传染性疾病
背景情况:
- 长期COVID经常导致持续的认知困难,影响感染后一年以上.
- 对长期COVID认知障碍缺乏基于证据的干预措施.
- 在其他神经疾病中成功的非药物治疗方案,需要对长期COVID进行受控试验.
研究的目的:
- 为了比较认知干预与长期COVID的认知行为咨询的有效性.
- 为了减少长期COVID患者的认知投诉.
- 评估干预措施对生活质量和社会参与的长期影响.
主要方法:
- 一个多中心,随机对照试验 (NCT05167266) 涉及130名患者.
- 患者在感染后至少三个月被招募,随机分别为1:1.
- 干预措施包括神经心理心理教育 (认知) 和情绪管理 (情感).
主要成果:
- 认知干预侧重于对疲劳,睡眠,注意力,记忆和执行功能的模块.
- 情感干预包括情感识别,不确定性管理和行为激活.
- 主要终点:干预后2个月的认知投诉减少,随访8个月.
结论:
- 非药物干预可能为长期的COVID认知问题提供低剂量,有效的策略.
- 该试验将确定最有效的干预类型,以改善长期COVID患者的认知功能和生活质量.
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