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Updated: Jul 18, 2025

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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在全身性硬化症中通过向早期生长反应1表达,通过Iguratimod减弱纤维化

Lichong Shen1, Hanlin Yin1, Li Sun2

  • 1Department of Rheumatology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200001, China.

Arthritis research & therapy
|August 18, 2023
PubMed
概括

伊古拉提莫德通过向纤维细胞的早期生长反应1 (EGR1) 表达,有效地减少系统性硬化 (SSc) 中的纤维化. 这种药物在改善皮肤纤维化和减少SSc模型中的原蛋白含量方面表现有前途.

关键词:
抗纤维性 抗纤维性早期生长反应 1 1在Iguratimod的使用中.系统性硬化症 系统性硬化症异种移植 异种移植

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