在使用阿片类药物的人群中检测阿片类药物过量剂量的可穿戴设备的可接受性有什么影响? 一个定性研究研究
Basak Tas1, Hollie Walker1, Will Lawn1,2,3
1National Addiction Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Drug and alcohol review
|August 19, 2023
概括
对于阿片类药物过量检测的可穿戴技术尚未得到充分理解. 使用阿片类药物的人 (PWUO) 发现不显眼,可访问和值得信赖的设备是可以接受的,但负担能力和技术访问仍然是障碍.
科学领域:
- 公共卫生 公共卫生
- 数字健康数字健康
- 药物使用研究研究 药物使用研究
背景情况:
- 在英国,与阿片类药物相关的死亡人数创下历史新高.
- 目前的过量抗药物,如纳洛,需要目击事件来管理.
- 在使用阿片类药物 (PWUO) 的人群中远程过量检测可穿戴技术的可接受性在很大程度上是未知的.
研究的目的:
- 在PWUO中探索可穿戴技术接受度的促进者和障碍.
- 了解PWUO对远程过量检测设备的偏好.
- 为开发可接受和有效的可穿戴过量检测技术提供信息.
主要方法:
- 与伦敦和诺丁汉的24个PWUO进行了半结构化访谈和焦点小组.
- 参与者目前或过去非法使用海洛因,有些人正在接受阿片类药物替代疗法.
- 专题分析用于分析记录和转录的关于可穿戴设备特征和偏好的对话.
主要成果:
- 可接受性受到特定于设备 (不显眼性),特定于个人 (针对子群体) 和特定于环境的因素 (负担能力,技术获取) 的影响.
- 对于区分高剂量和过量剂量的设备准确度的信任是关键促进因素.
- 技术提供商和PWUO之间缺乏信任成为一个重要的环境障碍.
结论:
- 可接受性的关键决定因素包括设备,人,环境因素.
- PWUO更喜欢那些不引人注目,舒适,易于使用,易于使用,准确,并由可信赖的组织提供的设备.
- 设备开发人员必须考虑最终用户的特性和环境环境,以提高可接受性.
相关概念视频
Opioid Analgesics: Synthetic and Semisynthetic Opioids
335
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
335
Opioid Receptors: Overview
1.0K
Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
1.0K
Analgesia and Pain Management
654
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
654
Opioid Analgesics: Morphine and Other Natural Cogeners
291
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
291
Pulse Oximetry
361
Pulse oximetry, or SpO2, is a non-invasive method for continuously monitoring arterial oxygen saturation (SaO2). This procedure involves attaching a probe or sensor to the patient's fingertip, forehead, earlobe, or nose bridge. The sensor works by detecting changes in oxygen saturation levels through light signals generated by the oximeter and reflected by the pulsing blood under the probe.
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
361
Drug Abuse and Addiction: Pharmacological Phenomena
512
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
512


