避免果汁被污染的策略 Alicyclobacillus acidocaldarius通过添加磁铁体/抗菌复合物来污染果汁
Jianrui Qi1, Hongfan Zhao1, Mengge Ning1
1College of Food Science and Engineering, Northwest A&F University, Yangling 712100, China.
Journal of agricultural and food chemistry
|August 19, 2023
概括
与抗菌酸 (MN@IDR-1018) 结合的磁基因组有效地抑制了果汁中的Alicyclobacillus acidocaldarius. 这种新型复合物具有低毒性,并且可以通过磁性回收,防止抗生素耐药性.
科学领域:
- 食品微生物学 食品微生物学
- 生物技术是生物技术.
- 材料科学是一种材料科学.
背景情况:
- 果汁在巴氏消毒后的生存率导致了果汁的重大经济损失.
- 目前的方法不足以完全防止A. acidocaldarius的腐烂,影响产品质量和保质期.
研究的目的:
- 开发和评估一种新型复合材料,MN@IDR-1018,用于抑制果汁中的A. acidocaldarius生长.
- 评估MN@IDR-1018复合物的抗菌疗效,毒性和对感官属性的影响.
主要方法:
- 合成MN@IDR-1018通过通过化将先天性防御调节器1018 (IDR-1018) 与磁体体 (MN) 结合.
- 确定针对A. acidocaldarius. 的最小抑制度 (MIC).
- 评估MN@IDR-1018在小鼠中的毒性及其对果汁颜色,风味和气味的影响.
- 从果汁中提取磁性的评估.
主要成果:
- MN@IDR-1018表现出强大的抗菌活性,对抗A. acidocaldarius,MIC为100μg mL-1.1.
- 复合物通过膜溶解和破裂诱导细菌细胞死亡.
- MN@IDR-1018在小鼠中表现出低毒性,并且没有改变果汁的感觉特性.
- 这种材料是有效地从果汁中使用磁场去除的.
结论:
- MN@IDR-1018是一种有前途的抗菌剂,可以防止果汁中的A. acidocaldarius腐烂.
- MN@IDR-1018的磁性可回收性提供了一个可持续的方法,减轻了发展抗生素耐药性的风险.
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