系统性硬化症的标准化死亡率:评估整体和性别和疾病亚型特定差异的元分析
1Department of Rheumatology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea (Republic of). lyhcgh@korea.ac.kr.
Zeitschrift fur Rheumatologie
|August 19, 2023
概括
系统性硬化症 (SSc) 患者的死亡率比一般人群高2.74倍. 这种增加的风险在男性和那些与有限的皮肤SSc (lcSSc) 相比,扩散皮肤SSc (dcSSc) 的患者中更高.
科学领域:
- 类风湿病学 类风湿病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 系统性硬化症 (SSc) 是一种具有显著发病率和死亡率的慢性自身免疫性疾病.
- 与一般人群相比,了解SSc患者的标准化死亡率 (SMR) 对风险分层和资源分配至关重要.
结论:
- 系统性硬化症与死亡风险相对于一般人群相比增加了近三倍.
- 性别和疾病亚型显著影响SSc患者的死亡风险,突出需要量身定制的管理策略.
- 在欧洲,北美,亚洲和大洋洲发现了SMR的地理差异,这表明了潜在的环境或医疗保健系统的影响.
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