基于纳米技术的真菌检测和治疗:现状和未来的前景
Vinay Chaudhari1, Vaishnavi Vairagade1, Ami Thakkar1
1Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's Narsee Monjee Institute of Management Studies, Mumbai, India.
Naunyn-Schmiedeberg's archives of pharmacology
|August 19, 2023
概括
纳米技术为诊断和治疗真菌感染提供了先进的解决方案,解决了诸如抗菌素耐药性和无效药物输送等挑战. 这种方法承诺更敏感的检测和人类真菌病的改善治疗结果.
科学领域:
- 医学诊断 医学诊断 医学诊断
- 纳米技术纳米技术
- 传染性疾病 传染性疾病
背景情况:
- 真菌感染对全球健康和医疗保健成本产生重大影响.
- 人类真菌菌,通常与SARS-CoV-2有关,经常被误诊.
- 菌中的抗菌素耐药性是一个越来越令人担忧的问题,特别是在医疗保健机构.
研究的目的:
- 审查用于真菌疾病诊断和治疗的纳米技术的最新进展.
- 突出纳米技术在克服当前抗真菌策略的局限性方面的潜力.
- 探索新的纳米诊断和基于纳米的治疗方法,用于菌病.
主要方法:
- 关于纳米技术在真菌学中的应用现有文献的综述.
- 为诊断和治疗目的分析纳米材料特性.
- 检查用于真菌检测和基于纳米的药物递送系统的纳米诊断技术.
主要成果:
- 纳米诊断能够准确和快速地分化和检测真菌疾病.
- 基于纳米的药物输送增强了药物的透性,减少了副作用,并改善了药物动力学特征.
- 纳米技术为对抗耐药性真菌病原体提供了有前途的战略.
结论:
- 纳米医学是一种可行的策略,可以解决真菌感染诊断和治疗中的关键问题.
- 新兴的纳米技术趋势为开发敏感诊断和有效治疗提供了创新工具.
- 纳米诊断和纳米治疗的进一步发展对于有效管理真菌疾病至关重要.
相关概念视频
01:29Microorganisms in Medicine and Therapeutics
54
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
54
01:29Overview of Fungi
54
Fungi are a diverse group of eukaryotes more closely related to animals than other eukaryotes. Fungal cell walls comprise chitin, a polysaccharide that provides structural strength, and glucans, which contribute to flexibility and integrity. Other polysaccharides, such as mannans and galactosans, may supplement or replace chitin in some fungi. These adaptations, along with their preference for acidic environments and tolerance for high osmotic pressure, enable fungi to thrive in various...
54