在超移动埃勒斯-丹洛斯或超移动性谱系障碍中喉腔病情的发病率
Stacey M Menton1, DeLisa Fairweather2,3,4, Katelyn A Bruno2,5
1Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Jacksonville, Florida, U.S.A.
The Laryngoscope
|August 19, 2023
概括
患有高移动性埃勒斯-丹洛斯综合征 (hEDS) 或高移动性谱系障碍 (HSD) 的患者会出现更高的语音,上呼吸道和吞问题. 这些症状比一般人群更为普遍.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 遗传学 遗传学 是一个
- 类风湿病学 类风湿病学
背景情况:
- 超移动性谱系障碍 (HSD) 和超移动性埃勒斯-丹洛斯综合征 (hEDS) 是一种结缔组织障碍,其特征是关节的超移动性.
- 喉病症,包括声音,上呼吸道和吞困难,可以显著影响生活质量.
研究的目的:
- 调查诊断为hEDS或HSD的患者喉腔病情的流行率和特征.
- 为了比较hEDS/HSD患者和对照组之间的这些投诉.
主要方法:
- 对363名患者 (289名hEDS/HSD患者,74名对照患者) 的回顾性分析,这些患者填写了关于语音,上呼吸道和吞症状的问卷.
- 收集的数据包括人口统计信息,语音相关症状和hEDS或HSD的诊断.
主要成果:
- 在hEDS和HSD组之间,语音障碍指数 (VHI-10) 分数或一般投诉没有显著差异.
- 与对照组相比,hEDS/HSD患者报告了对喉功能障碍问题的积极反应率较高 (p=0.031).
- 与一般人群数据相比,hEDS/HSD患者的声,食障碍和喉功能障碍症状的患病率较高.
结论:
- 患有hEDS或HSD的患者表现出更高的语音,上呼吸道和消化不良症状.
- 这些发现表明,超流动性障碍与特定的喉问题之间存在显著的关联,需要进一步的临床关注.
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