石英晶微平衡作为药物和建筑材料相互作用的预测工具,用于静脉注射蛋白质药物管理

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Updated: Jul 18, 2025

Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics
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Sample Preparation in Quartz Crystal Microbalance Measurements of Protein Adsorption and Polymer Mechanics

Published on: January 22, 2020

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Joseph Weidman1, Ligi Mathews2, Kedar Gokhale2

  • 1Janssen Pharmaceuticals, A Johnson & Johnson Company 1400 McKean Rd, Lower Gwynedd Township, PA 19002, USA.

Journal of pharmaceutical sciences
|August 19, 2023
PubMed
概括

这项研究量化了IV给药期间蛋白质药物对常见聚合物的损失. 一个预测模型估计了药物和表面活性剂对PVC和PP等表面的吸附,这对于配方特性至关重要.

关键词:
吸附方式 吸附方式 吸附方式抗体是药物中的一种抗体.药物与辅助剂的相互作用免疫治疗是一种免疫疗法.聚合物 聚合物 聚合物蛋白质聚合蛋白质的聚合.蛋白质配方是一种蛋白质配方.表面活性剂是一种表面活性剂.

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