患有甲状腺功能低下症的患者癌症的患病率:使用大数据工具进行分析
Juan J Díez1, Luis Cabrera1, Pedro Iglesias1
1Servicio de Endocrinología y Nutrición, Hospital Universitario Puerta de Hierro Majadahonda, Instituto de Investigación Sanitaria Puerta de Hierro Segovia de Arana, Majadahonda, Madrid, Spain; Departamento de Medicina, Universidad Autónoma de Madrid, Madrid, Spain.
Endocrinologia, diabetes y nutricion
|August 19, 2023
概括
甲状腺功能低下的诊断与60岁以下成年人患癌症的风险更高有关. 然而,这种关联在60岁以上的甲状腺功能低下患者中显著减少.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 大数据分析大数据分析
背景情况:
- 甲状腺功能低下症是一种常见的内分泌疾病.
- 甲状腺功能低下症和癌症风险之间的关系需要进一步调查.
研究的目的:
- 为了评估患有甲状腺功能低下症的患者的癌症发病率.
- 使用大数据探索与甲状腺功能低下症相关的癌症类型频率.
主要方法:
- 使用电子病历 (EMR) 的回顾性观察性研究.
- 大数据方法和人工智能用于数据提取.
- 在 Savana Manager 平台上进行的分析.
主要成果:
- 观察到甲状腺功能低下症和癌症频率增加之间存在显著的关联 (OR 2.09).
- 这种关联在男性和女性中都有,但在60岁以上的患者中没有.
- 在60岁以上的甲状腺功能低下患者中,特定癌症 (前列腺癌,肺癌,结肠直肠癌,肝癌) 的减少.
结论:
- 甲状腺功能低下的诊断与更高的癌症风险有关.
- 甲状腺功能低下症和癌症之间的关联在老年人 (60岁以上) 中较少明显.
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