在中国的精准医学中,制药护理模式是准确的
Ping Zheng1, Liqian Mo1, Boxin Zhao1
1Unidad de Farmacia Clínica, Hospital Nanfang, Universidad Médica del Sur, Guangzhou, China.
概括
精密药房通过整合基于证据的实践,药物基因组学和大数据来增强患者护理. 这种方法优化了个人患者的药物治疗,特别是那些患有复杂疾病的患者.
科学领域:
- 药理学和制药科学 药理学和制药科学
- 基因组学和个性化医学
- 临床药房实践 临床药房实践
背景情况:
- 药物反应的个体患者变化需要个性化药物护理.
- 在历史上,治疗药物监测 (TDM) 基于药理动力学 (PK) /药理动力学 (PD) 数据提供了个性化剂量.
- 药房实践的演变包括精准医学原则,结合基于证据的实践,PK/PD和大数据.
研究的目的:
- 概述精准医学的整合到药房服务中.
- 突出TDM和药物基因组学等先进方法在个性化药物护理中的作用.
- 描述精准药房对特殊患者群体的应用.
主要方法:
- 使用药理动力学/药理动力学 (PK/PD) 原则.
- 使用定量药理学和人口药理动力学.
- 利用大数据和机器学习来提供个性化药房服务.
- 整合药物基因组学分析.
主要成果:
- 精密药房服务越来越多地应用于抗微生物,抗瘤,抗精神病和免疫抑制药物治疗.
- 个性化服务是为高风险患者量身定制的,包括重症患者,药物相互作用风险,肝/功能不全,孕妇,儿童和老年人.
- 精密药房服务模型的开发和完善产生了新的临床证据.
结论:
- 精密药房代表了个性化药物护理的进步,超越了传统的TDM.
- 药物基因组学,PK/PD和大数据的整合使得针对不同患者群体进行量身定制的药物治疗成为可能.
- 精密药房服务的持续改进有望改善患者的治疗结果和证据生成.
关键词:
个性化药品医疗服务药物遗传学 药物遗传学个性化药品护理 个性化药品护理精准医学的医学药物治疗监控的方法药物基因组学 药物基因组学精准医学是一门精准的医学.精密药房服务 精密药房服务精密药房服务公司治疗药物监测 治疗药物监测更多相关视频
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