深度神经网络在甲状腺瘤病理分类中的价值
Chengwen Deng1, Dan Li2, Ming Feng3
1Department of Nuclear Medicine, Chaohu Hospital of Anhui Medical University, Heifei, 238000, China.
Diagnostic pathology
|August 19, 2023
概括
深度神经网络 (DNN) 在从病理图像中分类甲状腺瘤方面表现有前途,达到高精度. 这些模型为有效的甲状腺状况组织病理学诊断提供了潜力.
科学领域:
- 计算病理学计算病理学
- 医学中的人工智能.
- 甲状腺癌的诊断 甲状腺癌的诊断
背景情况:
- 深度神经网络 (DNN) 为分析复杂的病理图像提供了潜力.
- 准确诊断甲状腺瘤对于有效的治疗计划至关重要.
研究的目的:
- 为了评估甲状腺瘤病理学图像的DNNs的诊断价值.
- 探索DNN在甲状腺癌诊断中的临床应用潜力.
主要方法:
- 追溯分析了来自559名患者的799张甲状腺病理图像.
- 在四个DNN模型 (Resnet50,Resnext50,EfficientNet,Densenet121) 的培训和测试中.
- 包括各种甲状腺病理:乳头,髓,卵泡甲状腺癌,腺,腺瘤和正常甲状腺.
主要成果:
- DNN模型显示出高诊断效率,AUC高达0.994和卡帕系数高达0.7713.
- 记住,精度,NPV,准确性,特异性和F1分数在不同模型和病理学上有所不同.
- 在诊断卵泡性甲状腺癌,腺瘤和腺瘤囊时,观察到略低的性能.
结论:
- DNN模型在基于组织病理学图像的基础上对甲状腺瘤进行分类,取得了令人满意的结果.
- 这项研究强调了DNN在有效诊断甲状腺瘤组织病理学方面的潜力.
- 进一步的研究可能会对挑战性甲状腺病理的DNN性能进行改进.
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