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患者中CMV视网膜炎在mycophenolate免疫抑制:一个报告的两个病例
Prem N Patel1, Ahmed M Alkaliby2, Mitul C Mehta2
1Department of Ophthalmology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390-9057, USA. prem.patel@utsouthwestern.edu.
概括
细胞巨病毒 (CMV) 视网膜炎的风险增加与mycophenolate免疫抑制. 眼科医生应考虑降低或停止风险患者的mycophenolate以帮助病毒清除.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 免疫抑制是一种免疫抑制.
背景情况:
- 细胞巨乳病毒 (CMV) 视网膜炎的发病率增加与强效的免疫抑制疗法有关.
- 有证据表明,CMV感染和甲使用之间存在特定的关联.
- 这项研究调查了接受mycophenolate的患者的CMV视网膜炎.
研究的目的:
- 报告两例CMV视网膜炎的病例,这些病例发生在接受菌酸盐免疫抑制治疗的患者中.
- 为了突出与甲相关的CMV感染的潜在增强脆弱性.
主要方法:
- 介绍了两个不同的CMV视网膜炎患者病例.
- 临床表现的详细描述,包括底镜检测结果.
- 对免疫抑制疗法的审查,重点是菌酸盐的使用.
主要成果:
- 这两名患者均呈现出与CMV视网膜炎一致的临床症状.
- 这两位患者都接受了菌酸盐免疫抑制药物治疗.
- 他们提出了减少或停止甲治疗的建议.
结论:
- 菌酸的免疫抑制可能会增加对CMV感染的易感性,包括视网膜炎.
- 眼科医生必须认识到,在服用菌酸盐的患者中,这种风险增加.
- 在与其他专家协商后,调整酸剂量可能有助于CMV清除.
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