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Updated: Jul 18, 2025

An Integrated Platform for Genome-wide Mapping of Chromatin States Using High-throughput ChIP-sequencing in Tumor Tissues
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HDAC2和SMAD3-SKI之间的表观遗传和分子协调调节了脑瘤干细胞的基本特征

Ravinder K Bahia1,2, Xiaoguang Hao1,2, Rozina Hassam1,2

  • 1Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

Nature communications
|August 19, 2023
PubMed
概括

海斯脱乙酶2 (HDAC2) 是通过改变色素来促进脑瘤干细胞生长和自我更新的关键. 针对HDAC2-SMAD3-SKI通路提供了一个有前途的质母细胞瘤治疗策略.

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