高分辨率的模拟和测量表明,在人类心脏周期中,B0振荡式时空波动
Yun Shang1, Sebastian Theilenberg1, Martin Gajdošík1
1Department of Biomedical Engineering, Columbia University in the City of New York, New York, New York, USA.
Magnetic resonance in medicine
|August 20, 2023
概括
这项研究验证了一种新的模拟方法,用于在心脏周期期间心脏中的磁场 (B0) 分布. 模拟准确地预测了体内观察到的B0模式,改善了心脏MRI质量.
科学领域:
- 磁共振成像是一种磁共振成像技术.
- 生物物理学的生物物理.
- 心血管成像 - 心血管成像
背景情况:
- 使用平衡稳定状态自由先行序列的心脏MRI容易出现由B0不均性引起的暗带工件.
- 准确的B0分布的表征对于心脏MRI中人工物减少和图像质量改善至关重要.
研究的目的:
- 通过使用结构性MRI数据,在整个心脏周期中模拟人心中的B分布.
- 为了验证这些模拟与体内测量的心脏相位特异性B0地图在3T.
主要方法:
- 在3T时从8名健康受试者获得心脏阶段特定的B0场地图.
- 模拟的B0条件使用来自结构和解剖MRI扫描的组织口罩.
- 将模拟与体内测量进行比较,使用空间和时间相关性分析.
主要成果:
- 在整个心脏周期中,在模拟和测量B0地图之间实现了0.91的平均空间相关系数.
- 在模拟和体内测量中观察到一致的高水平B0模式.
- 证明了B0变异的强烈时间相关性,表现出形特征.
结论:
- 经过验证的理论B0模拟使用区域解剖特征与体内B0映射相比.
- 证实了空间B0条件在整个心脏周期中因心脏运动诱导的结构扭曲而振荡.
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