相关实验视频

Updated: Jul 18, 2025

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
05:08

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins

Published on: July 8, 2025

91

ETLD:一种编码器-转换层-解码器架构,用于蛋白质接触和突变效应预测

He Wang1, Yongjian Zang1, Ying Kang1

  • 1MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an 710049, China.

Briefings in bioinformatics
|August 20, 2023
PubMed
概括

我们开发了一种新的自我监督模型,即编码器-转换层-解码器 (ETLD) 架构,以从蛋白质多重序列对齐 (MSA) 中提取潜在特征. ETLD有效地预测了残留接触和突变效应,优于现有的方法.

关键词:
联系 预测 联系 预测编码器-转换层-解码器 (ETLD) 模型多重序列对齐 (MSAs) 是指多个序列对齐.突变效应的预测和预测转换矩阵的转换矩阵.

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