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贫血和异常性内高血压:一个前性研究

Amir R Vosoughi¹, Irina Sverdlichenko², Edward Margolin³

¹Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie

|August 20, 2023

概括

大约20%的异常性内高血压 (IIH) 患者也患有贫血,超过10%的人患有严重的贫血. 中度至重度的贫血可能需要手术干预,这突显了在IIH诊断中全血细胞计数的重要性.

科学领域:

神经学神经学
眼科医生眼科眼科
血液学血液学血液学

背景情况:

异常性内高血压 (IIH) 疑似与贫血有关,但之前的研究缺乏前性数据.
在肥胖的年轻女性中,IIH和贫血都很普遍,复杂化了病因学的理解.
由于常见的危险因素,贫血和IIH之间的关系需要进一步调查.

研究的目的:

为了前性地调查诊断为IIH的患者中贫血的患病率和特征.
为了确定贫血是否影响IIH患者的临床表现或治疗需求.
评估在怀疑IIH的个人中进行常规贫血查的必要性.

主要方法:

这是一项从2021年3月到2022年9月在三个神经眼科中心进行的前性研究.
包括连续IIH患者,在呈现后六个月内进行完整血清 (CBC).
贫血被分类为轻度 (110~120 g/L),中度 (80~109 g/L) 或严重 (<80 g/L).

主要成果:

在143名IIH患者中,有30人 (21%) 患有贫血,其中13.3%患有严重贫血.
在贫血和非贫血组之间没有观察到性别,年龄,BMI,视力敏度或视网膜神经纤维层厚度的显著差异.
患有中度至重度贫血的患者表现出需要手术治疗的趋势 (p=0.045).

结论:

大约20%的IIH患者患有贫血,其中很大一部分患有中度至重度贫血.
贫血,特别是中度至重度的贫血,可能与IIH中外科手术干预的需求增加有关.
建议对所有怀疑IIH的患者进行常规CBC检测,因为贫血的发病率很高.

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