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在nulliparas中持续的胎盘前期的风险因素和围产期结局
Rebecca J Post1, Jenny Chang2, Argyrios Ziogas3
1Department of Obstetrics and Gynecology, University of California, Irvine, Irvine, CA (Drs Post, Crosland, and Chung).
American journal of obstetrics & gynecology MFM
|August 20, 2023
概括
在无胎儿的个体中,母亲的年龄较大,先前的怀孕流产和体外受精增加了持续性胎盘前期的风险. 这种情况与更高的早产和剖腹产率有关.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 生殖医学 生殖医学
背景情况:
- 在怀孕中期诊断的胎盘前往往会在第三个三个月内消失.
- 在无产妇妇女中,持续性胎盘前的危险因素尚不清楚.
- 多胞胎和先前的剖腹产是已知的持续性胎盘前期的危险因素.
研究的目的:
- 为了确定持续的胎盘前置的风险因素,在无胎儿的个体.
- 为了比较持久和解决的胎盘前列在nulliparas之间的结果.
主要方法:
- 预期无卵性妊娠结果研究的二次分析:监测即将成为母亲的队列 (nuMoM2b).
- 包括10,037名无胎儿的个体,中期的胎盘前诊断.
- 使用多变量逻辑回归来分析风险因素和结果.
主要成果:
- 在17%的中期胎盘前的nulliparas中,在分娩时有持续的前.
- 持续性风险因素包括母亲年龄较大,先前的怀孕流产 (<20周),以及体外受精 (IVF).
- 持续的胎盘前期与增加的产前住院,早产和剖腹产相关.
结论:
- 较年长的孕产妇年龄,先前的怀孕流产和试管婴儿是无孕妇女持续性胎盘前置症的重要危险因素.
- 持续的胎盘前与不良分娩结果有关,但与整体妊娠或新生儿结果无关.
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